GHRP-6

Overview

GHRP-6 (Growth Hormone Releasing Peptide 6) is a synthetic hexapeptide — a chain of six amino acids with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. Its molecular formula is C₄₆H₅₆N₁₂O₆, and it has a molecular weight of 873.01 g/mol. The CAS registry number is 87616-84-0. Like GHRP-2, the peptide features an amidated C-terminus and contains D-amino acids (D-Trp and D-Phe), which are mirror-image versions of the naturally occurring L-forms. These D-amino acids make the peptide more resistant to enzymatic breakdown.

GHRP-6 was first synthesized in the 1980s, making it one of the earliest synthetic growth hormone releasing peptides ever created. It was the compound that originally demonstrated that small synthetic peptides were structurally compatible with what is now known as the growth hormone secretagogue receptor (GHS-R1a), a receptor later associated with the stomach hormone ghrelin. GHRP-6 is classified as a growth hormone secretagogue and ghrelin mimetic. It is supplied as a white to off-white lyophilized powder that dissolves readily in water.

This product is strictly for research purposes only. Not approved for human or animal use.

PubChem Reference: View compound profile on NIH PubChem